Physiological features of primary hemostasis in cows during pregnancy kept in the conditions of central Russia

The functional parameters of blood vessels and platelets are great biological importance throughout the life animal. Their activity is designed to provide necessary level rheological properties in small medium caliber. In work carried out cows during pregnancy, a decrease sensitivity stimulators platelet was revealed. This, apparently, leads them pregnancy curb adhesion aggregation platelets. A hemostatic largely due weakening expression on their surface receptors that can bind inducers fibrin, thromboxane synthesis, inhibition myosin formation actin formation, secretory release adenosine phosphates from granules cells. plates phospholipases A2 C. Strengthening disaggregation associated with an intensification synthesis walls deaggregants prostacyclin nitric oxide, which enhance trophism fetal tissues. Changes primary hemostasis develop as proceeds characteristics increase functionality vascular element hemostasis, providing optimal conditions for capillary perfusion active anabolism growing fetus.